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pentobarbital will lessen the extent or effect of brexpiprazole by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Double brexpiprazole dose over one-2 months if administered with a strong CYP3A4 inducer.Contraindicated (1)pentobarbital will lessen the level or effect of doravirine by influencing hepatic/intest